Path of Exile 2 Poisonous Concoction Pathfinder Guide

In Path of Exile 2 (PoE2), Poisonous Concoction is a versatile build combining efficient map clearing and exceptional single-target damage. This guide provides detailed insights into gear choices, passive tree optimizations, and gem setups to help you craft the ultimate Poisonous Concoction Pathfinder.

1. Key Features of the Poisonous Concoction Pathfinder

Single-Target Damage

With its poison-stacking mechanics and chaos damage, Poisonous Concoction excels in boss fights. The built-in poison cloud effect allows for massive damage in a short period.

Outstanding Map Clearing

By triggering corpse explosions with the Decompose skill, this build can clear large areas quickly. It performs exceptionally well in game mechanics such as Breach and Delirium.

Exceptional Movement Speed

The character boasts a base movement speed of 54.8%, which increases to 78% when swapping to the off-hand setup. This speed makes it one of the fastest builds in the game.

2. Core Gear Overview

1. Main Equipment

• Corpsewade Iron Greaves

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  • Provides the Decompose skill, generating green poison clouds that deal 38.5% of the corpse's maximum life as chaos damage.
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  • Its base movement speed is only 10%, so pairing it with Queen of the Forest is essential.
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• Queen of the Forest

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  • Grants 1% increased movement speed per 500 evasion rating.
  • With 27,000 evasion on the main hand, it offers 54% movement speed, increasing to 78% with 39,000 evasion on the off-hand setup.
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• Widowhail

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  • Enhances skill damage and can be corrupted for even greater damage boosts.
  • Adding a +15 Spirit Rune slot can further improve stats but is expensive, costing approximately 140 Exalted Orbs.

2. Quiver

• Primary Attributes:

  • +2 to Projectile Skill Levels (most important).
  • Increased attack speed and bow skill damage (currently functional for Poisonous Concoction, possibly due to a bug).

• Secondary Attributes:

  • Dexterity to meet gem requirements.
  • Projectile speed for smoother gameplay.

When unequipped, the DPS is 2,569, but equipping the quiver raises it to 4,937.

3. Other Gear

• Helmet (Pain Ward):

  • Focus on high energy shield and resistances.
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• Amulet (Blight Locket):

  • +3 to Projectile Skill Levels.
  • Maximum energy shield and life boosts.
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• Ring (Ming's Heart):

  • Adds 40% chaos damage at the cost of 20% reduced maximum life and 30% reduced global defenses, which is still worthwhile for this build.
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3. Gem Setup

Main Skill: Poisonous Concoction

• Linked Gems:
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  • Scattershot
  • Deadly Poison
  • Chaos Mastery
  • Chaos Infusion

Supporting Skills

• Vine Arrow for additional poison damage.

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  • Consider Swift Affliction or Font of Rage as link options.
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• Dark Effigy to apply Wither, increasing chaos damage taken.

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• Despair combined with Focus Curse to reduce enemy resistances.

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Additional Configurations

• Bind specific skills to different weapon sets:
  • Main-hand for combat.
  • Off-hand for enhanced movement speed.

4. Passive Tree and Ascendancy

Core Passives

• Poison duration: Prolong poison effects for more overall damage.
• Weapon swap nodes: Boost evasion and movement speed using dual-weapon setups.
  • Key Node: +2 evasion per maximum energy shield on equipped helmet.

Ascendancy Priority

• Nature’s Boon: Enhances flask efficiency.
• Veteran Bowyer: Amplifies projectile and poison damage.

5. Gameplay Tips and Optimization

Boss Fight Strategy

1. Place Dark Effigy to apply Wither, stacking up to 70% increased chaos damage taken.
2. Use Vine Arrow to trigger poison stacking and additional chaos damage.
3. Spam Poisonous Concoction for high single-target damage.

Map Clearing Strategy

• Leverage poison clouds and corpse explosions for efficient map clearing.
• Switch to the off-hand setup for faster movement between packs.

Optional Gear

• Snakebite Gloves: Increases maximum poison stacks from 8 to 10, boosting damage by approximately 25%.
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• Gem Swaps: Use Magnified Effect to increase the range of Poisonous Concoction.

The Poisonous Concoction Pathfinder offers a blend of high mobility and explosive damage, making it an adaptable and powerful build. By stacking evasion and energy shield, and optimizing weapon swaps, this setup excels in both map clearing and boss fights. If you enjoy fast gameplay and strategic positioning, this build is worth trying!

Watch the Build in Action:

Check out the full guide and gameplay on YouTube.

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